Definition of an open fracture
To treat open fractures effectively, we need to understand what they are and how they occur.
What is an open fracture?
Open fractures are also referred to as exposed or compound fractures.
An open fracture is a broken bone that has a direct communication between the fracture site and the external environment through a wound in the skin and/or soft tissues1,2. In simple terms: there is both a break in the bone and a skin wound that exposes the fracture or its hematoma to the outside world.
Example - Even a very small skin puncture (from a sharp bone fragment poking out from the inside) qualifies the injury as an open fracture.
The disruption of both the bone and surrounding soft tissues leads to exposure to external contaminants such as dirt, bacteria, and other microorganisms. This exposure significantly increases the risk of infection1. Severe soft tissue damage further hinders normal healing by impairing blood circulation, which can prevent the fracture site from receiving adequate nourishment and oxygen3.

Open Fracture of the Tibia
Management of open fractures poses a serious challenge to surgeons, both in high and low resource settings, despite recent advances in treatment protocols3. The most dangerous early complication is death due to blood loss. The most common complication is fracture related infection, potentially leading to sepsis, tissue necrosis and high risks on delayed and non-union of the fracture4.
The aim of treatment of open fractures is to enable healing of bone and other tissue involved with a good functional outcome. An open fracture can only be adequately managed when both bone and soft tissue components are treated1.
Open fractures are surgical emergencies.
The sooner the treatment is provided, the better the outcome because it reduces the infection risk. That's why open fractures are medical emergencies, especially if they present early (which is almost always the case in high income settings). When patients present late (days or weeks after the injury), already with signs of sepsis, this is of course also an emergency. If the patient presents late without signs of sepsis, there is more time to optimize the patients' general condition and to plan the treatment with the best possible team in your setting1.
Take into account that the timing of surgery should be a balanced decision between:
1 The need to act fast and
2 The time needed to be able to provide the best possible treatment, preferable by an experienced orthoplastic team.
1 Roberts, L., Ahmed, M. R., & Agrawal, D. K. (2025). Current Strategies in the Prevention and Management of Infection in Open Fractures. Journal Of Orthopaedics And Sports Medicine, 218–229. https://doi.org/10.26502/josm.511500198 Available from:
2 Sop, J. L., & Sop, A. (2023, 8 augustus). Open Fracture Management. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK448083/ Available from:
3 Dheenadhayalan, J., Nagashree, V., Devendra, A., Velmurugesan, P. S., & Rajasekaran, S. (2023). Management of open fractures: A narrative review. Journal Of Clinical Orthopaedics And Trauma, 44, 102246. https://doi.org/10.1016/j.jcot.2023.102246 Available from:
4 Hannigan, G. D., Pulos, N., Grice, E. A., & Mehta, S. (2014). Current Concepts and Ongoing Research in the Prevention and Treatment of Open Fracture Infections. Advances in Wound Care, 4(1), 59–74. https://doi.org/10.1089/wound.2014.0531 Available from:
Joost Binnerts, Nienke Smits, Abeba Aleka Kebede
Experts: Pieter Haasnoot
Editors: Job Wernand, Pim Bongers, Eva Alkemade, Matthijs Botman, Renz Wierper.